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Chlorine Dioxide Medical Device Sterilization: Residual Toxicity Testing
December 2, 2025
Ethylene oxide (EtO), a commonly used sterilant for medical devices, is a known carcinogen that leaves carcino- genic residuals. Recent regulatory changes encourage medical device manufacturers to consider non-carcinogenic sterilants, including chlorine dioxide (ClO2) sterilization.
PEER REVIEWED ARTICLE
Chlorine dioxide gas sterilization of cold-chain or temperature-sensitive devices
August 27, 2026
Cold-chain terminal sterilization is used for products that must be manufactured, stored, and maintained with a carefully controlled temperature range, such as temperature-sensitive drugs and vaccines in prefilled syringes or autoinjectors containing temperature-sensitive drugs.
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PEER REVIEWED ARTICLE
Chlorine Dioxide Medical Device Sterilization: Residual Toxicity Testing
December 2, 2025
Ethylene oxide (EtO), a commonly used sterilant for medical devices, is a known carcinogen that leaves carcino- genic residuals. Recent regulatory changes encourage medical device manufacturers to consider non-carcinogenic sterilants, including chlorine dioxide (ClO2) sterilization.
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PEER REVIEWED ARTICLE
Residual Testing on a Medical Device
November 10, 2021
Since the use of chlorine dioxide to sterilize medical devices is fairly new, the acceptable levels of ClO2 residue left on medical devices after the sterilization process has never been defined. The following study was carried out in order to determine how much (if any) ClO2 residue is present subsequent to a ClO2 sterilization cycle.
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PEER REVIEWED ARTICLE
Block Book Chlorine Dioxide
December 5, 2019
Chlorine dioxide is a yellow-green gas that was first prepared by Chenevix in 1802. Humphrey Davy independently prepared this compound in 1811, elucidated its composition, and proposed the name of euchlorine.
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